OneDrive Error Codes

How to Fix RPC Server Unavailable Error Opening Large OneDrive Files

Emma BrownEmma Brown Oct 15, 2026 869 views

Question details

Users receive an RPC Server Unavailable error when trying to open large files from synchronized OneDrive or SharePoint folders.

How to Fix RPC Server Unavailable Error When Opening Large OneDrive Files
Product
Microsoft OneDrive and SharePoint
Device & OS
not provided
Scenario
Opening files around 500 MB or larger directly from a local synchronized OneDrive or SharePoint directory.
Observed behavior
The first attempt to open the file fails with an RPC Server Unavailable error. A second attempt to open the same file may succeed, and the issue can impact multiple users across the network.
Before you start

Before proceeding, attempt to open the file a second time, as the connection might establish successfully on subsequent attempts. You should also check your network stability to rule out temporary connection drops.

Solution 1Recommended

Escalate the Issue to Microsoft 365 Support

Since this synchronization error often impacts multiple clients and involves backend service timeouts with large files, opening a formal support ticket is the most effective resolution.

When large files (500 MB+) fail to open on the first attempt across multiple client machines, the issue is typically rooted in the Microsoft 365 tenant environment or the underlying OneDrive synchronization service. Microsoft Support has the backend access required to investigate and resolve these tenant-specific anomalies.

1
Document the synchronization details

Gather necessary information including the exact file sizes causing the error, the number of affected client machines, the specific timing of the errors, and any local troubleshooting steps you have already tried.

2
Contact your Microsoft 365 Administrator

Reach out to your organization's IT department or designated Microsoft 365 administrator, as standard users cannot access the advanced admin support portals.

3
Create a support request

Have the administrator log into the Microsoft 365 Admin Center, navigate to the Support section, and create a new service request detailing the RPC Server Unavailable error.

Escalate the Issue to Microsoft 365 Support
Information Required for Support: Providing detailed logs and confirming that the issue affects multiple users will help Microsoft Support escalate and investigate your tenant environment much faster.
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Frequently Asked Questions

Why does the RPC Server Unavailable error primarily affect large files?

Large files, such as those over 500 MB, require more time and bandwidth to synchronize. If the background synchronization service times out or struggles to handle the data payload during the initial open request, it fails to communicate with the server, triggering the RPC error.

Will trying to open the file a second time permanently fix the issue?

Opening the file a second time often succeeds because the initial request prompted the synchronization service to cache or process the file in the background. However, this is only a temporary workaround, and the error will likely reappear for other large files until the underlying tenant issue is resolved by Microsoft.

Does this RPC error happen in both OneDrive and SharePoint?

Yes, because both OneDrive and SharePoint rely on the same underlying Microsoft synchronization engine for local file access, large files synced from either platform can trigger the RPC Server Unavailable error.