OneDrive File Issues

Fix Make Sure OneDrive Is Running Error When Opening Files

Maira Mehtab Sep 21, 2026 868 views

Question details

The user is unable to open files, such as AutoCAD drawings, stored in their local OneDrive folder because of a synchronization error prompt.

Product: OneDrive
Device & OS: not provided
Scenario: Attempting to open synced files from a local OneDrive directory into a desktop application.
Observed behavior: The file fails to open and displays a message stating 'Make sure OneDrive is running', even though OneDrive is actively running and backing up files. Unlinking and relinking the account did not fix the problem.

Before you start

Verify that your internet connection is active and that your device is logged into the correct Microsoft account within the OneDrive application.

Solution 1Recommended

Set the File to 'Always Keep on This Device'

Force OneDrive to download a local copy of the file to bypass online-only access issues.

OneDrive functions as a cloud storage location, which means files in the folder may be 'online-only' placeholders to save local disk space. When third-party applications like AutoCAD try to access an online-only file, the system may throw a 'Make sure OneDrive is running' error because the file isn't physically available on the hard drive yet.

Locate the File

Open Windows File Explorer and navigate to your OneDrive folder where the problematic file is stored.

Change File Availability

Right-click the specific file (such as your AutoCAD drawing) and select 'Always keep on this device' from the context menu.

Wait for Synchronization

Watch the file's status icon. Wait for it to change to a solid green circle with a white checkmark, indicating the local download is complete.

Open the File

Double-click the file to open it directly into your application without triggering the error.

Offline Availability: Files marked with a solid green checkmark can be opened anytime, even if you are disconnected from the internet or if OneDrive is temporarily closed.

Solution 2

Verify OneDrive Sync Status and Account Settings

Ensure OneDrive is actively syncing the correct account to prevent cross-account file access errors.

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Frequently Asked Questions

Why does my PC say 'Make sure OneDrive is running' when the application is already open?

This typically occurs when a program attempts to access an 'online-only' file before OneDrive has finished downloading the necessary background data. Setting the file to 'Always keep on this device' forces a full local download and resolves the issue.

What do the different OneDrive file status icons mean?

A blue cloud indicates the file is online-only and requires an internet connection to open. A green checkmark with a white background means the file is locally available on a temporary basis. A solid green circle with a white checkmark means the file is permanently downloaded to your device.

Can I open online-only OneDrive files without an internet connection?

No, online-only files require an active internet connection so the system can download the file data. If you need to work offline, you must right-click the files while connected and select 'Always keep on this device'.

Does unlinking and relinking my OneDrive account delete my local files?

No, unlinking your PC from OneDrive only pauses the synchronization process and disconnects the account. Your local files and online files remain completely intact. Once you relink your account, synchronization will safely resume.

Document & File Issues