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Fix Office 365 Email Rejected by Gmail (Error 550 5.7.350)

John WilsonJohn Wilson Oct 7, 2026 868 views

Question details

The user is attempting to send emails from a custom domain hosted on Microsoft 365 to Gmail recipients but faces delivery failures due to authentication issues.

How to Fix Office 365 Email Rejected by Gmail (Error 550 5.7.350)
Product
Microsoft 365 / Exchange Online
Device & OS
not provided
Scenario
Sending outbound email messages from a custom Microsoft 365 domain to Gmail accounts.
Observed behavior
Emails are rejected by Gmail and returned as suspected spam, generating SMTP error 550 5.7.350 because domain authentication (SPF, DKIM, DMARC) is incomplete or incorrect.
Before you start

Ensure you have administrative access to both your Microsoft 365 Admin Center and your domain's DNS hosting provider (such as GoDaddy, Cloudflare, or Namecheap) to modify the necessary domain records.

Solution 1Recommended

Configure SPF, DKIM, and DMARC Records for Microsoft 365

Properly setting up these three email authentication protocols will verify your domain's identity to Gmail, removing the spam suspicion and resolving the 550 5.7.350 error.

Gmail has implemented strict sender guidelines that require all external domains to be fully authenticated. Error 550 5.7.350 means Gmail could not verify that your email legitimately came from your domain.

1
Set up the SPF Record

Log in to your DNS provider's dashboard. Create a new TXT record for your domain with the host set to '@' and the value 'v=spf1 include:spf.protection.outlook.com -all'. This authorizes Microsoft 365 to send emails on your behalf.

2
Generate DKIM Keys in Microsoft 365

Navigate to the Microsoft 365 Defender portal. Go to 'Policies & Rules' > 'Threat Policies' > 'DomainKeys Identified Mail (DKIM)'. Select your custom domain and choose the option to create DKIM keys. The system will generate two CNAME records.

3
Publish DKIM Records

Take the two CNAME records generated by Microsoft 365 and add them to your DNS provider's settings. Once saved, return to the Defender portal and enable the toggle to 'Sign messages for this domain with DKIM signatures'.

4
Configure DMARC Alignment

In your DNS provider, create a new TXT record with the host '_dmarc' and the value 'v=DMARC1; p=quarantine; rua=mailto:your-email@yourdomain.com;'. This tells Gmail how to handle emails that fail SPF or DKIM checks.

Configure SPF, DKIM, and DMARC Records for Microsoft 365
DNS Propagation Time: After adding these records, it can take anywhere from 15 minutes to 48 hours for the DNS changes to propagate globally. Wait for propagation before testing email delivery to a Gmail account.
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Frequently Asked Questions

Why does Gmail suddenly reject emails from my Office 365 domain?

Gmail frequently updates its spam protection policies and now strictly requires sending domains to use SPF, DKIM, and DMARC authentication. If your domain lacks these records or they are misconfigured, Gmail blocks the messages to protect users from spoofing and phishing.

Can I resolve Error 550 5.7.350 without accessing my DNS settings?

No, resolving this error requires modifying your domain's DNS zone files to add the necessary authentication records. If you do not have administrative access, you will need to contact your IT administrator or your domain hosting provider for assistance.

How can I verify that my SPF, DKIM, and DMARC records are working?

You can use free online DNS checker tools like MxToolbox or the Microsoft Remote Connectivity Analyzer. These tools allow you to input your domain and will quickly analyze if your SPF, DKIM, and DMARC records are correctly published and aligned.