Fix Microsoft 365 Not Opening After Windows 10 Pro Install
Question details
User is unable to open Microsoft Word, Excel, and PowerPoint after installing Windows 10 Pro, and standard reinstallation from the account page does not resolve the problem.
- Product
- Microsoft 365
- Device & OS
- Windows 10 Pro
- Scenario
- Attempting to access and run Office applications following a new Windows OS installation.
- Observed behavior
- Microsoft 365 applications fail to open, and performing a basic reinstall from the Microsoft account page yields no changes.
Before proceeding, verify that your Microsoft 365 subscription is currently active by logging into your Microsoft account, and ensure you have administrator privileges on your Windows 10 Pro system.
Perform a Clean Uninstall and Reinstall of Microsoft 365
Since a basic reinstall did not work, you must completely remove corrupted Office files left behind during the Windows 10 Pro upgrade before attempting to install again.
Standard reinstallations often fail if corrupted registry keys or conflicting background services remain on the system. A complete removal followed by a restart ensures a clean slate.
Navigate to 'Settings' > 'Apps' > 'Apps & features' in Windows 10 Pro. Locate Microsoft 365 in the list, click on it, and select 'Uninstall'. Follow the prompts to remove the suite.
Once the uninstallation is complete, restart your Windows 10 Pro device. This step is critical as it clears lingering temporary files and resets registry keys.
Go to www.office.com/myaccount and sign in with the Microsoft account associated with your active subscription. Click 'Install Office' and run the downloaded setup file to reinstall.
Run the Microsoft Support and Recovery Assistant (SaRA)
Use Microsoft's official diagnostic tool if a manual clean installation does not resolve the issue.
Try WPS Office for Seamless Productivity on Windows 10 Pro
If Microsoft 365 continues to face installation conflicts on your new Windows 10 Pro system, consider switching to WPS Office. It provides a highly compatible, free, and lightweight alternative to Microsoft Office, allowing you to open, edit, and save your Word, Excel, and PowerPoint files without interruption.
- 1. Download WPS Office: Visit the official WPS Office website and download the free installer for Windows.
- 2. Install the Application: Run the downloaded file and follow the quick setup wizard to install WPS Office on your Windows 10 Pro device.
- 3. Open Your Files: Launch WPS Office and directly open your existing Word, Excel, and PowerPoint documents with perfect formatting preservation.

Frequently Asked Questions
Why won't my Microsoft 365 apps open after installing Windows 10 Pro?
Upgrading or reinstalling an operating system can sometimes disrupt software registry paths, permissions, or background services required by Microsoft 365, causing the apps to fail upon launch.
Will uninstalling Microsoft 365 delete my saved documents?
No. Uninstalling Microsoft 365 only removes the application files from your computer. Your locally saved Word documents, Excel spreadsheets, and PowerPoint presentations remain safe on your hard drive.
How can I verify if my Microsoft 365 subscription is still active?
You can check your subscription status by signing in to www.office.com/myaccount with your Microsoft credentials and navigating to the 'Services & subscriptions' section.
What should I do if the Microsoft Support and Recovery Assistant cannot fix the issue?
If the official diagnostic tool fails, you may need to check for conflicting third-party antivirus software, verify Windows updates are fully installed, or consider using a highly compatible alternative like WPS Office to access your files immediately.




