How to Fix Excel and Access Not Opening After a Windows Update
Question details
The user is unable to launch Microsoft Excel and Access after installing a recent Windows update, even when attempting to open the applications in Safe Mode.

- Product
- Microsoft Office Professional 2016
- Device & OS
- Windows
- Scenario
- Attempting to open Excel or Access spreadsheets and databases following a recent Windows OS system update.
- Observed behavior
- Excel and Access fail to start or launch completely, while Word and PowerPoint continue to function normally. Excel also refuses to start in Safe Mode.
Ensure your computer has an active internet connection, as advanced repair options require downloading replacement files from Microsoft, and save any ongoing work in Word or PowerPoint before proceeding.
Run an Office Program Repair from Control Panel
Using the built-in Windows repair tool is the most reliable way to fix corrupted Office program files caused by recent system updates.
Since Excel fails to open even in Safe Mode, the issue is likely rooted in corrupted core application files or a system-level glitch rather than a conflicting add-in. Running a Quick Repair or an Online Repair will restore these essential files without deleting your personal data.
Click the Start menu, type 'Control Panel', and press Enter. Change the view to Large Icons, then click on 'Programs and Features'.
Scroll through the list of installed applications until you find 'Microsoft Office Professional 2016' or your specific Office version.
Right-click the Microsoft Office entry and select 'Change'. If prompted by the User Account Control, click 'Yes' to allow changes.
Select the 'Quick Repair' option and click 'Repair'. Wait for the process to finish and try opening Excel. If the apps still do not open, repeat this process and choose 'Online Repair'.

Install Pending Windows and Office Updates
Microsoft often releases subsequent patch updates to fix compatibility bugs introduced by previous updates.
Switch to WPS Office for a Stable, Hassle-Free Spreadsheet Experience
If Windows updates frequently break your Microsoft Office installation, consider switching to WPS Office. It is a lightweight, highly stable, and completely free alternative that opens and edits all your existing Microsoft Excel, Word, and PowerPoint files natively without the headache of constant repair loops.
- 1. Download the Installer: Visit the official WPS Office website and click the 'Free Download' button.
- 2. Install the Software: Run the downloaded installer and follow the quick on-screen instructions.
- 3. Open Your Excel Files: Right-click any problematic Excel file, choose 'Open with', and select WPS Office to view and edit your data instantly.

Frequently Asked Questions
Why does Excel fail to open even in Safe Mode?
If an application fails to launch in Safe Mode, it typically indicates that the core program files, dependencies, or registry keys have been corrupted—usually by a failed or conflicting system update—rather than being caused by a faulty third-party add-in.
Will running an Office Repair delete my personal files?
No. The Repair tool in Windows only checks and replaces corrupted application files belonging to Microsoft Office. Your personal documents, spreadsheets, and databases are completely safe and will not be affected.
Can third-party antivirus software block Excel and Access from opening?
Yes. Sometimes, security software may incorrectly flag a newly updated Office executable file as a threat, preventing it from launching. You can try temporarily disabling your antivirus to see if the applications open normally.




