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Office Apps Not Opening

Fix Excel Files Opening as Blank Window After Microsoft 365 Installation

Kushani NimanthikaKushani Nimanthika Sep 27, 2026 869 views

Question details

The user is unable to view older Excel files properly because they open to a blank window, and Excel is missing from the "Open With" menu.

How to Fix Excel Files Opening as a Blank Window After Installing Microsoft 365
Product
Microsoft Excel
Device & OS
not provided
Scenario
Opening legacy XLS and XLSX files after a new installation of Microsoft 365, potentially alongside an older version of Microsoft Office.
Observed behavior
Excel files open briefly and then display a completely blank Excel window. Additionally, Excel is missing from the "Open With" list for XLS and XLSX file formats.
Before you start

Ensure you have saved all ongoing work and closed any hidden Excel background processes via the Task Manager. Check your installed programs list to verify if multiple versions of Microsoft Office are currently installed on your computer.

Solution 1Recommended

Uninstall Conflicting Microsoft Office Versions

Removing older versions of Microsoft Office (like Office 2010) prevents conflicts with Microsoft 365 and restores proper file associations.

There is no separate Excel 2010 file format; Excel 2007 and later use the same XLS and XLSX formats. Having multiple versions of Office installed simultaneously is a primary cause of file association errors and blank screens.

1
Open Control Panel

Press the Windows key, type 'Control Panel', and press Enter. Navigate to 'Programs' and select 'Programs and Features'.

2
Locate Installed Office Versions

Scroll through the list of installed applications and look for multiple Microsoft Office entries (e.g., Microsoft Office Professional 2010 and Microsoft 365).

3
Uninstall the Older Version

Right-click the older or unnecessary Microsoft Office version and select 'Uninstall'. Follow the on-screen prompts to remove it completely.

4
Restart Your Computer

Once the uninstallation is complete, restart your PC and try opening your XLS or XLSX file again to see if it opens normally.

Uninstall Conflicting Microsoft Office Versions
Seek Professional Help for Registry Changes: If standard uninstallation fails, you may need to clean up registry keys. Consider seeking professional assistance before modifying the Windows Registry manually.
Free Microsoft Office alternative

Avoid Office Version Conflicts with WPS Office

If repairing Microsoft 365 is taking too much time or you want a lightweight solution free of version conflicts, consider switching to WPS Office. It effortlessly handles all legacy and modern Excel files without complicated system configurations.

  1. 1. Install WPS Office: Download and install the free WPS Office suite from the official website.
  2. 2. Open WPS Spreadsheet: Launch WPS Spreadsheet from your desktop or start menu.
  3. 3. Load Your Excel File: Click 'Menu' > 'Open' and select your XLS or XLSX file to view and edit its contents immediately.
Highly compatible with Microsoft Excel formats including XLS, XLSX, and CSV.Lightweight software that installs quickly and doesn't conflict with existing system apps.Completely free to use with a familiar, easy-to-navigate tabbed interface.Seamlessly open blank or problematic spreadsheets that fail to load in other suites.
microsoft office alternative - wps office

Frequently Asked Questions

Why does Excel open a blank grey screen when I double-click a file?

A blank grey screen usually occurs when file associations are corrupted by conflicting Office installations, or if the setting 'Ignore other applications that use Dynamic Data Exchange (DDE)' is enabled in Excel's Advanced options.

Can I have Microsoft 365 and Excel 2010 installed on the same computer?

While it is technically possible, running multiple versions of Office frequently causes file association conflicts and issues like blank windows. It is highly recommended to uninstall older versions and keep only one installation.

How do I add Excel back to the 'Open With' menu if it is missing?

You can restore it by right-clicking your Excel file, selecting 'Choose another app', and browsing your PC for the EXCEL.EXE file located in your Program Files > Microsoft Office folder. Make sure to check the box to 'Always use this app'.

Is there a specific Excel 2010 file format I need to convert?

No. Excel 2007, 2010, and all newer versions including Microsoft 365 use the exact same XLSX format for standard workbooks, and support the legacy XLS format. No file conversion is necessary.